SkinCeuticals Advanced RGN-6

A regenerative serum designed to support skin repair, resilience, and visible recovery.

RGN-6 is an advanced restorative treatment formulated to support the skin’s natural repair processes. Developed for use during periods of increased skin stress — including post-procedure recovery, visible aging, and barrier compromise — this serum helps improve skin strength, smoothness, and overall quality over time.

Rather than targeting a single concern, RGN-6 focuses on skin regeneration as a whole, making it an essential product for patients seeking improved texture, tone, and resilience with minimal irritation.

Why It’s Different

RGN-6 is built around a multi-pathway regenerative approach. Its formulation supports skin recovery by helping to:

• Strengthen the skin barrier

• Improve visible texture and firmness

• Support collagen signaling and renewal

• Reduce signs of stress and inflammation

This makes it especially valuable during post-treatment phases, seasonal skin changes, or periods when skin needs restoration rather than correction.

Who This Product Is Best For

• Extremely sensitive skin

• Post-procedure recovery

• Early to advanced signs of aging

• Compromised or sensitized skin

• Patients seeking skin strengthening and repair

• Those who cannot tolerate aggressive actives

Pregnancy use should be reviewed with a provider.

When to use

• Evening use is preferred

• Can be used once daily or as directed by your provider

Where it fits in your routine

• Apply after cleansing

• Use as your targeted treatment step

• Follow with hydration and moisturizer

On nights when RGN-6 is used, it should typically be the only corrective treatment applied.

How much to use

• 1–2 pumps

• Apply evenly to face and neck

• Press gently into the skin rather than massaging aggressively

Important guidance
RGN-6 is ideal for recovery and regeneration nights. It can be alternated with exfoliating or acne-focused treatments rather than layered on the same evening.

Regenerative Peptide Complex
Supports cellular communication involved in skin repair and renewal, helping improve visible firmness and smoothness over time.

Proxylane™
A patented SkinCeuticals ingredient shown to help support skin density and elasticity by reinforcing the skin’s structural matrix. Particularly beneficial for aging or compromised skin.

Niacinamide
Strengthens the skin barrier, improves uneven tone, and helps reduce inflammation. Supports tolerance to other treatments and enhances overall skin resilience.

Glycerin + Humectant Blend
Provides sustained hydration, improving comfort and supporting optimal conditions for repair and regeneration.

Soothing Botanical Extracts
Help calm visible redness and irritation, making the formula suitable for sensitive or post-procedure skin.